Systane Eye Drops: Which Type Is Right for You?

Compare contact-safe and preservative-free options, plus when to consider a dry eye evaluation

Systane eye drops are lubricating drops that can help relieve dry, irritated eyes. The best option depends on whether you wear contacts, want preservative-free drops, or need a thicker formula for persistent dryness. Use the quick guide below to choose—and if symptoms keep coming back, a dry eye evaluation can identify what’s really causing it.

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What Are Systane Eye Drops Good For?

Dry, burning, and irritated eyes can disrupt your daily life. Systane eye drops are designed to:


✔️ Relieve dryness, redness, and discomfort
✔️ Provide long-lasting hydration for irritated eyes
✔️ Protect against further irritation and damage
✔️ Improve comfort for contact lens wearers
✔️ Reduce sensitivity to light and environmental irritants


No matter the cause—screen time, allergies, or aging—Systane eye drops help restore moisture and keep your eyes feeling refreshed.

Experienced & Skilled Team

Our highly trained professionals provide expert care, utilizing the latest techniques for optimal eye health and aesthetics.

Personalized Care

We tailor our services to meet your unique needs, ensuring you receive individualized attention and customized solutions.

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Which Systane Eye Drops Should I Choose?

Choose the Right Systane Eye Drops (Mini-Guide)

  • If you wear contacts: Choose Systane eye drops that are labeled contact-lens friendly and follow the directions on the package. In general, many people use Systane eye drops before inserting lenses to improve comfort, and after removing lenses to rehydrate and calm irritation at the end of the day. If your lenses feel dry during wear, it’s a sign to confirm the drop is specifically approved for use with contacts and to rule out an underlying dry eye issue.


  • If you want preservative-free: A preservative-free (PF) Systane eye drops option is often preferred by people with sensitive eyes or anyone who wants a gentler feel—especially if they’re using Systane eye drops more frequently. Preservative-free formulas can be a good fit when your eyes sting easily, you’re prone to irritation, or you simply want a frequent-use style of lubrication without added preservatives.


  • If dryness is persistent: If your symptoms don’t fade quickly—or you wake up with gritty, burning eyes—look for Systane eye drops in a thicker or gel-like style designed for longer-lasting coverage. These options can feel more cushioning and may provide extended relief, but it’s normal to notice temporary blur right after applying thicker Systane eye drops, especially if you use them before driving or screen work.



  • If you’re using drops daily: If you need Systane eye drops every day (or multiple times a day), it’s a smart time to book a dry eye evaluation at Frame Bar. Co. In-office, we check what’s actually driving your symptoms—how stable your tear film is, whether tears are evaporating too quickly, and whether eyelid or surface irritation is contributing—so you’re not stuck guessing which Systane eye drops to keep reaching for long-term.

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Systane for Contacts: What to use and how to apply

If you wear contact lenses and deal with dryness, Systane for contacts can be a simple way to improve comfort—especially during long workdays, screen time, or dry indoor air. The key is choosing Systane eye drops that are specifically labeled as safe for contact lens wear, and using them in a way that keeps your eyes comfortable without guesswork.


For many contact lens wearers, the easiest approach is using Systane for contacts before you put your lenses in to start the day with better moisture, and after you remove your lenses to rehydrate your eyes and calm irritation. If you want to use Systane for contacts while your lenses are in, only do so when the product label says it’s compatible with contacts, and follow the directions on the packaging. If the drops cause noticeable stinging, blur that doesn’t clear quickly, or your eyes feel worse instead of better, stop using them and check in with an optometrist.


If you’re unsure which Systane for contacts option is compatible with your specific lenses, bring the bottle to your visit at Frame Bar. Co. We can help you confirm what you’re using, talk through when to apply it (before, during, or after lens wear), and make sure your dryness isn’t coming from an underlying dry eye issue that needs a more targeted plan.

When drops aren’t enough

  • If symptoms return quickly after using Systane eye drops
  • If you’re using Systane eye drops daily (or more than once a day)
  • If you have a burning or gritty sensation that persists
  • If contacts feel uncomfortable often, even with Systane for contacts
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How Do Systane Eye Drops Help With Dry Eye Symptoms?

Dry eye syndrome occurs when your eyes don’t produce enough high-quality tears to stay properly lubricated. This can result in redness, irritation, excessive tearing, and even vision disturbances. Factors like prolonged screen time, aging, and environmental conditions can make symptoms worse.


Systane eye drops work by replenishing moisture and stabilizing the tear film, which consists of three key layers:


  • The Mucin Layer – Helps tears spread evenly over the eye’s surface.
  • The Aqueous Layer – Provides hydration and nutrients to the cornea.
  • The Lipid Layer – Prevents rapid tear evaporation.


When these layers are disrupted, Systane eye drops help restore balance by replacing lost moisture and reducing inflammation. They also create a protective barrier that prevents further damage from dry air, wind, and allergens.


Unlike some artificial tears that only provide temporary relief, Systane eye drops are scientifically designed to address the root causes of dry eye, ensuring long-lasting hydration and comfort.

What Are the Side Effects of Using Systane Eye Drops?

While Systane eye drops are generally safe and well-tolerated, some users may experience mild side effects. These effects are usually temporary and subside as the eyes adjust to the drops. The most common side effects include:


  • Temporary blurred vision immediately after application
  • Mild eye redness or discomfort
  • Increased sensitivity to light
  • Watery eyes or stickiness around the eyelashes
  • Swelling of the eyelids (rare cases)


Most people do not experience side effects, but if you notice persistent irritation, burning, or worsening symptoms, you should stop using the drops and consult an optometrist.


At FrameBar.co, we don’t just provide Systane eye drops—we offer comprehensive dry eye care. If over-the-counter drops aren’t enough, we can assess your condition and recommend advanced treatment options tailored to your needs.

Why Choose FrameBar.co for Your Eye Care Needs?

At FrameBar.co, we don’t just sell Systane eye drops—we provide expert eye care solutions for long-term relief. Our team, led by Dr. Vincente Calderón, specializes in dry eye diagnosis and treatment, ensuring that you receive the best possible care for your vision health.


Here’s why FrameBar.co is your best choice for dry eye solutions:

  • Expert Recommendations

    Our optometrists help you choose the right Systane eye drops based on your specific symptoms.

  • Advanced Dry Eye Treatment

    If over-the-counter drops aren’t enough, we offer professional solutions to treat the root cause of your discomfort.

  • Comprehensive Eye Exams

    We assess your eye health and screen for underlying conditions contributing to dry eye.

  • Convenient Location & Personalized Service

    Visit us at FrameBar.co in Oceanside, NY, for personalized eye care in a welcoming environment.

Dry eye can significantly impact your daily life, but with the right treatment, you can restore comfort and clarity. Let us help you find the best solution for your eyes.

Frequently Asked Questions About Systane Eye Drops

  • Can I use Systane eye drops every day?

    Yes! Systane eye drops are safe for daily use. However, if your symptoms persist despite regular use, consult our optometrists to rule out underlying issues.

  • Are Systane eye drops safe for contact lens wearers?

    Some Systane formulas, like Systane Ultra and Systane Hydration, are safe for contact lenses. Always check the packaging or ask our team for guidance.

  • How long do Systane eye drops last after opening?

    Most Systane eye drops are safe to use for three months after opening. Always follow storage instructions and avoid contaminating the dropper tip.

  • Can I use Systane eye drops before sleeping?

    Yes! Systane Gel Drops provide overnight moisture and protection, making them ideal for nighttime use.

  • Where can I buy Systane eye drops?

    You can purchase Systane eye drops directly at FrameBar.co in Oceanside, NY. Visit us for expert guidance and premium eye care products.

  • Which Systane is best for contacts?

    The best Systane for contacts is the one that’s clearly labeled as compatible with contact lenses and matches when you need relief. Many people get great comfort by using Systane eye drops before inserting lenses and after removing them, because that supports moisture without interfering with the lens on the eye. If you want to use Systane for contacts while your lenses are in, stick to a product that specifically says it can be used with contacts and follow the package directions. If you’re not sure which bottle you have—or which Systane for contacts option fits your lens type—bring it to your visit at Frame Bar. Co so we can help you confirm compatibility and usage.

  • What’s the difference between Systane Contacts and preservative-free options?

    Systane Contacts is positioned around contact lens wear, meaning it’s intended to be used in a way that supports lens comfort (and, depending on the exact product label, may be compatible during lens wear). Preservative-free (PF) Systane eye drops are focused on gentleness—often preferred by people with sensitive eyes or anyone using Systane eye drops more frequently who wants a preservative-free formula. The easiest way to choose is to match your priority: if your main issue is contact lens comfort, start with a Systane for contacts option that’s labeled for contacts; if your main issue is sensitivity or frequent use, a preservative-free Systane eye drops option may feel better. If you’re trying to balance both, bring the product you’re using and we’ll help you pick the most appropriate approach for your eyes and your lens routine.

  • When should I use thicker drops (gel) instead of regular drops?

    Thicker, gel-like Systane eye drops are often a better fit when dryness feels persistent, your eyes feel gritty or burning for long stretches, or you tend to feel worse later in the day. These thicker Systane eye drops can provide longer-lasting coverage than regular drops, but it’s normal to have temporary blur right after applying them—so many people prefer using gel-style drops when they don’t need immediate clear vision (like at home, after removing contacts, or before bed if the label allows). If you find yourself needing thicker Systane eye drops regularly, or if relief doesn’t last, that’s a strong signal to book a dry eye evaluation at Frame Bar. Co so we can identify what’s driving your symptoms and recommend a more targeted plan.

Visit Frame Bar. Co for Dry Eye Treatment

If you’re experiencing symptoms of dry eye, don’t wait for discomfort to worsen. Our team at Frame Bar. Co in Oceanside, NY, is dedicated to providing you with effective solutions for dry eye syndrome. We are committed to restoring your comfort and enhancing your quality of life through tailored treatment plans.

A young girl is getting her eyes examined by an ophthalmologist. - systane eye drops
March 14, 2025
Looking for lasting relief from dry eye symptoms? Discover how Systane eye drops can restore moisture and comfort. Visit FrameBar.co for expert eye care solutions today!
A woman is applying eye drops to an older man 's eye for dry eye treatment
March 14, 2025
Suffering from dry, irritated eyes? Frame Bar. Co in Oceanside, NY, offers expert dry eye treatment to restore comfort. Call us today to book an appointment!

Take the First Step Toward Relief From Dry Eye Symptoms.

If dry, irritated eyes are affecting your quality of life, FrameBar.co has the solution. Whether you need Systane eye drops for quick relief or a more comprehensive treatment plan, we’re here to help.


Call us today at (516) 888-1038 or Book an Appointment Online to schedule your evaluation. Let us help you find the right treatment for your dry eyes and regain your comfort and clarity.

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